Chromatography and Analytical Techniques

Nanochromatography Innovations

Nanochromatography is an emerging field that enables high-resolution analysis using ultra-low flow rates and micro- to nano-scale columns. With increased sensitivity and reduced sample requirements, nanochromatography is particularly advantageous in proteomics, metabolomics, and biomarker discovery, where sample volumes are often limited. Coupled with mass spectrometry (nanoLC-MS), it delivers precise quantitation and detailed molecular profiling. Innovations in nano-scale column fabrication, fluidic control systems, and sample injection techniques have significantly improved reproducibility and robustness. These developments make nanochromatography a powerful tool in cutting-edge biomedical and pharmaceutical research. The reduced solvent consumption also aligns with green analytical chemistry principles, offering both environmental and cost benefits. Automated platforms now integrate sample preparation, separation, and detection into miniaturized systems, ideal for high-throughput laboratories and field-based applications. This session explores the latest trends in nanochromatography, from nanoLC-MS instrumentation to its transformative applications in personalized medicine, clinical diagnostics, and next-generation therapeutic research, illustrating its growing impact on precision analytical methodologies.