Chromatography and Analytical Techniques

Clinical Diagnostics Applications

Chromatography has become a cornerstone of modern clinical diagnostics, offering high specificity and sensitivity for detecting biomarkers, metabolites, and therapeutic drugs in biological matrices. Techniques such as LC-MS/MS and GC-MS are routinely used for therapeutic drug monitoring, hormone analysis, and toxicology screening. These methods enable rapid and accurate identification of disease states, patient compliance with medications, and early detection of metabolic disorders. The emergence of microfluidic and automated sample preparation systems has streamlined workflows in hospital and clinical laboratories. Additionally, bioanalytical method validation ensures diagnostic accuracy and supports regulatory compliance. In recent years, the demand for personalized medicine has driven the development of multiplexed chromatographic platforms capable of simultaneously measuring multiple analytes in small sample volumes. With integration into laboratory information systems (LIS) and support from artificial intelligence for data interpretation, chromatography is poised to further transform point-of-care testing and centralized lab diagnostics. This session highlights the innovations, regulatory perspectives, and clinical significance of chromatographic methods in diagnostics, reinforcing their indispensable role in advancing precision healthcare.