8^th World Congress on Chromatography September 13-14, 2018 Prague, Czech Republic | Panorama Hotel Prague | Milevská 7, 140 63 Praha

Mr. Miroslav Ryska (1938) holds an undergraduate degree from Charles University, along with an M.S. in Physical Chemistry from Moscow State University and a PhD. from the Institute of Macromolecular Chemistry of Czechoslovak Academy of Sciences. From 1961 to 1978 he worked at the Institute of Macromolecular Chemistry of the Czechoslovak Academy of Sciences. In 1978 - 1997 he worked as a researcher in the field of MS and its application in research of metabolism and pharmacokinetics of drugs at the Research Institute for Pharmacy and Biochemistry in Prague. He has written more than 100 publications mainly on the topic of mass spectrometry, trace analyses, analyses of drugs, metabolites and quantitative analysis. In the 1990’s Mr. Ryska acted as an Editor of two international journals, The Journal of Mass Spectrometry and Rapid Communication in Mass Spectrometry. He founded Quinta-Analytica s.r.o.in 1997 and currently holds the position of Vice President.

Bioanalysis, Pharmacokinetics, Bioequivalence and Mass Spectrometry

Dr. Norberto Guzman received a B.Sc. degree in biochemistry from the University of Chile, Santiago, Chile; a M.Sc. degree in biochemistry (cell and molecular biology) from the Medical College of Georgia, Augusta, Georgia, U.S.A.; and a Ph.D. degree in biochemistry from a Joint Graduate Program of the University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School and Rutgers, The State University of New Jersey, New Brunswick, New Jersey, U.S.A. Dr. Guzman has worked for the last 30 years in academic medical institutions, diagnostic and pharmaceutical companies, including Mount Sinai School of Medicine, Roche Diagnostic Systems, Hoffman-La Roche, and Johnson & Johnson. He is currently the Chief Scientific Officer-Director of Research at Princeton Biochemicals, Inc. Princeton, New Jersey, U.S.A.

Dr. Norberto Guzman main research interest is in the studies of protein biomarkers in biological fluids using miniaturized immunoaffinity capillary electrophoresis instruments.

Gilles Goetz is a Principal Scientist at Pfizer in Groton, Connecticut, USA. Gilles received his B.Sc. (1991) and Ph.D. (1995) at the University of Strasbourg in France. After post docs at the University of Hawaii (1996-97) and of Neuchatel (CH) (1998-99) studying marine and fungal natural products, he joined Monsanto in 2000. There he worked through mergers and acquisitions for Pharmacia and Pfizer successively in the Natural Product group, the HTS group (analytical support), and the Purification Group. In 2010 he transferred to the Expert Purification Group at Pfizer Groton and in 2011 to the Molecular Properties Group. He is part of the team influencing medicinal chemistry design through insights into molecular properties such as polarity, lipophilicity, shape, and conformation that will impact molecular behaviors like solubility, permeability, and efflux. They develop and use mainly chromatographic techniques (EPSA) to assess those properties, and work towards predicting molecular behaviors.

SFC, HPLC applications, Immobilized Artificial Membrane (IAM) chromatography as well as Micellar Liquid Chromatography (MLC), along with EPSA

Employed at Polymer Institute, Slovak Academy of Sciences in Bratislava. Served as elected member of the Presidium of the Slovak Academy of Sciences, President of the Slovak Chemical Society, Chairman of the Czecho-Slovak and Slovak National Committee of Chemistry for IUPAC. Corresponding member of the Central European Academy of Sciences and member of the Learned Society of the Slovak Academy of Sciences. Author or co-author of two monographs and 250+ scientific papers in extenso published in refereed periodicals, proceedings and chapters of books, as well as 60+ patents (four of them were licensed) - cited more than 2,000x. Presented over 110 invited plenary, key and main lectures, as well as over 900 regular lectures and poster contributions on symposia and conferences and during lecturing tours to over fourty countries. Elected „Slovak scientist of the year 1999“ and „Slovak innovator of the year 2001“.

Polymer sciences, Separation Sciences, HPLC Close

Károly Héberger Ph.D., Cand. Sci., D.Sc., t.Prof.. in his early carrier he investigated liquid phase oxidation (radical) processes, and determined rate constants by kinetic ESR spectroscopy. Later he studied Quantitative - structure activity (property) relationships. QSAR, QSPR and QSRR. Now he deals with chemometrics: multivariate data evaluation techniques, principal component analysis, stepwise linear regression, partial least squares regression, variable selection, model building and validation, pattern recognition (supervised and unsupervised), classification of food products, clustering, method comparison and ranking, etc. His scientific results were presented in more than 160 papers (including book chapters) and more than 300 lectures (or posters). Hirsch index=34 and i-10=index 83 (Web of Sci). The papers were cited above 3500 times (without self - citations and cross - references). More information can be found at: http://aki.ttk.mta.hu/scientist/heberger/

Chemometrics;Data evalutions in chromatography, Method comparisons, modeling and validation, clustering, ranking

Dr. Xue obtained her M.D. from the Shanghai Second Military Medical University in 1983, Ph.D. from the Institute of medical Sciences and Department of Biochemistry, University of Toronto in 1992, and carried out postdoctoral studies at the Department of Genetics, University of Glasgow before joining the Department of Biochemistry, Hong Kong University of Science & Technology (HKUST). Currently, Dr. Xue is Director of Applied Genomics Center of HKUST, and Professor of Life Science at Hong Kong University of Science and Technology. Dr. Xue’s group research focuses on genomics, bioinformatics and evolution biology to decipher the mechanisms of human complex diseases, in particular, schizophrenia. The group is also interested in translational research on novel therapeutics and diagnostics for complex neuropsychiatric disorders including anxiety, depression and neurodegenerative disorders, with a focus on GABAA receptors as the drug targets. In order to effectively isolate active components from medicinal herbs, her group has recently developed a novel chromatographic method designated as Disbursed Mobile-Phase Countercurrent Chromatography (DMCC). In 2003, Dr. Xue and her team discovered the association between schizophrenia and a segment of the GABRB2 gene encoding the -subunit of GABAA receptors, the positive selection of genotypes and haplotypes in this segment, determinant role of this segment in the alternate splicing of the subunit protein, and the differential modulation of the GABA-induced membrane current by the long and short forms. These discoveries represent therefore the first instance where a schizophrenia-susceptibility gene has been linked to protein processing and further to electrophysiological response of neurons, thereby opening the door toward understanding the mechanism of schizophrenia etiology leading from gene to neuronal phenotype.

Genomics, Bioinformatics and Evolution biology

Dr Abbas Amini is an assistant professor at the Australian College of ACK and Western Sydney University, and the member of graduate supervisory board. After obtaining PhD, he conducted research with other Australian universities, as a postdoctoral research fellow at Monash and Deakin Universities, and as a senior research fellow at the University of Melbourne. His fine outcomes have been presented in high impact factor journals, e.g., Nature publication group, and a recent published book in 2016. Abbas is the editor of ten reputed journals, and the committee member of 20 international conferences.

Bionanotech

Prof. Ravi Bhushan has an expertise in enantiomeric resolution of compounds of pharmaceutical importance using liquid chromatography. So far, he has guided 28 doctoral and 50 Masters’ theses, published more than 230 research papers in international refereed journals and chapters in books and encyclopedia. He edited four Special Issues of Biomedical Chromatography on Chiral Resolutions as Guest Editor. He received Alexander von Humboldt fellowship of Germany in 1988, and European Economic Community Fellowship in 1992. He is an elected Fellow of the Royal Society of Chemistry, London, and Fellow National Academy of Sciences India, (FNASc). He received the ‘Outstanding Teacher Award’ of the year 2007 of IIT Roorkee, and Khosla Research Prize and Silver Medal of Univ of Roorkee.

Ravi Bhushan current interest includes enantioseparation with both achiral phases of chromatography in the absence of any external chiral species.