Tuzimski T
Medical University in Lublin, Poland
Title: Optimization of extraction conditions, identification and quantitative analysis of xenobiotics (e.g., pesticides, dyes, bisphenols) in natural and biological samples and food products using high-performance liquid chromatography (HPLC) combined with modern detection techniques (DAD, MS, MS/MS)
Biography
Biography: Tuzimski T
Abstract
Bisphenols are a class of chemicals with two hydroxyphenyl functionalities, which include bisphenol A (BPA) and several analogues such as BPS, BPB, BPF, BADGE, BADGE • 2H2O, BADGE • 2HCl. As industrial chemical, BPA is widely used in the production of polycarbonate (PC) plastics (used in food contact materials, such as food containers, baby food and water bottles), epoxy resins (used as internal coating in canned food and beverage to prevent the food to get in contact with the metal wall and the deterioration of cans) and as an antioxidant in polyvinyl chloride (PVC) plastics in materials intended to come into contact with food (packaging cling films). Due to endocrine disruptor potential and estrogenic activity of the compound, the BPA release from packaging or storage containers into foods and beverages is a great public health concern. The release of BPA into the food depends on the type, pH and lipid content of food, temperature, and contact time. Due to their fat content, both breast and dietary milk could be polluted by many xenobiotics characterized by lipophilic properties. Milk and dairy products are widely consumed by infants, children, and many adults throughout the world, and occurrence of quantifiable amounts of BPA represents a matter of public health concern. European Commission (EU) has established a migration limit of 0.6 mg/kg for BPA in food or food simulant from plastic materials and articles intended to come in contact with foodstuffs (Regulation (EU) No. 10/2011) and has interdicted the BPA use in the fabrication of baby bottles (Regulation (EU) No.321/2011). Considering that many estrogenic effects caused by BPA occur at concentrations below the recommended safe daily exposure and that children are particularly vulnerable, a new risk assessment has been strongly recommended for consumer health protection. The aim of the paper was determination of xenobiotics (BPA and its analogues, pesticides, dyes) in natural and biological samples (e.g., breast milk) and food products.