Chromatography and Analytical Techniques

Multidimensional chromatography

Both comprehensive two-dimensional gas chromatography (GCxGC) and comprehensive two-dimensional liquid chromatography (LCxLC) have developed as capable tools for expanding the peak limit of a solitary chromatographic analysis. Using orthogonal chromatographic systems, analytes can be isolated by two unique, successive maintenance systems; this procedure takes into consideration analytes to be isolated from different compounds that would regularly co-elute in a solitary dimensional separation. Endeavors at NIST are being coordinated toward the investigation of issues identified with quantitation by both GCxGC and LCxLC, esteem task of complex matrix Standard Reference Materials (SRMs), and non-targeted analysis.